What is Fucoidan?
Fucoidan (pronounced foo-koy-den) is a complex polysaccharide found in many species of brown seaweed. Fucoidan has been researched extensively for its bioactive benefits. Many studies at renowned organizations around the world (such as PubMed, Oxford Journals) have found that fucoidan may have the ability to promote quality of life. The substance found in the cell walls of certain seaweed species is used medicinally for a wide variety of health purposes such as treating high blood pressure, infections, or allergies.
“Fucoidan contains galactose, glucoronic acid, xylose and several other major constituents that give the substance its potential health benefits” – Memorial Sloan-Kettering Cancer Center
Consult with your doctor before you begin using fucoidan to discuss the right dosage for you and as well as the potential side effects, drug interactions, and other health risks.
What makes Imperial Fucoidan?
The composition of sulfated polysaccharides, minerals, and fucose.
These are important factors when it comes to selecting the best Fucoidan. Our fucoidan is obtained entirely from minerals and pigments, to produce a nutritional supplement that is one of a kind.
* The Food & Drug Administration has not yet assessed these statements. Imperial Fucoidan is not intended to diagnoses, treat, cure, or prevent any disease. This information is provided for your reference only.
Imperial Fucoidan and Cancer
References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413214/
Abstract
There is a wide variety of cancer types yet, all share some common cellular and molecular behaviors. Most of the chemotherapeutic agents used in cancer treatment are designed to target common deregulated mechanisms within cancer cells. Many healthy tissues are also affected by the cytotoxic effects of these chemical agents. Fucoidan, a natural component of brown seaweed, has anti-cancer activity against various cancer types by targeting key apoptotic molecules. It also has beneficial effects as it can protect against toxicity associated with chemotherapeutic agents and radiation.
Thus the synergistic effect of fucoidan with current anti-cancer agents is of considerable interest. This review discusses the mechanisms by which fucoidan retards tumor development, eradicates tumor cells and synergizes with anti-cancer chemotherapeutic agents. Challenges to the development of fucoidan as an anti-cancer agent will also be discussed.
1. Introduction to Cancer
Cancers are multifactorial diseases of various etiologies. They arise largely as a result of acquired genetic changes that alter cell function leading neoplastic cells to gain survival or growth advantages [1]. For cancer cells to survive, the generation of new blood vessels (angiogenesis) is required. Cancer leads to death mostly through tumor cell spread to distal organs (metastasis). Various pathways are disrupted in tumor development, which result from unbalanced programmed cell death, disordered signaling pathways, angiogenesis and poor immune response against cancer. Most of the chemotherapeutic agents used in cancer treatment target these major deregulated pathways. Unfortunately, as many of these therapies cause severe side effects, the toxicities limit the dose and thus the efficacy of treatment. Therefore, there is strong interest in developing better-tolerated anti-cancer agents.
